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NY-87-13-4 -- Enthalpy Recovery in Low-Humidity Pharmaceutical Clean Rooms

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NY-87-13-4 -- Enthalpy Recovery in Low-Humidity Pharmaceutical Clean Rooms

Conference Proceeding by ASHRAE, 1987

M. Viscovich, P.E.

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Manufacturing of pharmaceutical products must comply with FDA requirements and the industryâs own standards. The humidity, temperature, and particulate and microbial quality of the air must be controlled in the manufacturing "controlled environment area" to ensure that the drug product retains its purity. A once-through air-conditioning system and low relative humidity are frequent requirements in controlled environments where the product is exposed to the atmosphere (weighing, mixing, filling, or transfer).

This paper will examine air-to-air energy exchange where both sensible and latent heats are transferred between airstreams (enthalpy recovery). The impact on initial cost, energy saving, and air cleanliness will be considered. Enthalpy recovery by chemical absorption can have an acceptable payback. It reduces the refrigeration load and provides operating savings along with filtration for both supply and exhaust airstreams.

Units: I-P

Citation: Symposium, ASHRAE Transactions, 1987, vol. 93, pt. 1, New York, NY

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Published: 1987 Number of Pages: 14File Size: 1 file , 1.1 MB Product Code(s): D-NY-87-13-4